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1

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

Pentel, Paul R., Raleigh, Michael D., LeSage, Mark G., Thisted, Thomas, Horrigan, Stephen, Biesova, Zuzana, Kalnik, Matthew W.

Journal:

BMC Biotechnology

Year:

2018

Language:

english

File:

PDF, 2.15 MB

english, 2018

2

The TEAM project: the effectiveness of smoking cessation intervention with hospital patients

Deborah J. Hennrikus, Harry A. Lando, Maribet C. McCarty, David Klevan, Neal Holtan, Jacquelyn A. Huebsch, Sharon Jestus, Paul R. Pentel, Donald Pine, Susan Sullivan, Karen Swenson, John Vessey

Journal:

Preventive Medicine

Year:

2005

Language:

english

File:

PDF, 488 KB

english, 2005

3

Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC–MS assay for delayed analyses of pharmacokinetic samples in rats

Jessica M. Jones, Michael D. Raleigh, Paul R. Pentel, Theresa M. Harmon, Daniel E. Keyler, Rory P. Remmel, Angela K. Birnbaum

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2013

Language:

english

File:

PDF, 548 KB

english, 2013

4

Effects of portion size on chronic energy intake

Robert W Jeffery, Sarah Rydell, Caroline L Dunn, Lisa J Harnack, Allen S Levine, Paul R Pentel, Judith E Baxter, Ericka M Walsh

Journal:

International Journal of Behavioral Nutrition and Physical Activity

Year:

2007

Language:

english

File:

PDF, 179 KB

english, 2007

5

Portion size effects on weight gain in a free living setting

French, Simone A., Mitchell, Nathan R., Wolfson, Julian, Harnack, Lisa J., Jeffery, Robert W., Gerlach, Anne F., Blundell, John E., Pentel, Paul R.

Journal:

Year:

2014

Language:

english

File:

PDF, 141 KB

english, 2014

6

Negatively Charged Carbon Nanohorn Supported Cationic Liposome Nanoparticles: A Novel Delivery Vehicle for Anti-Nicotine Vaccine

Zheng, Hong, Hu, Yun, Huang, Wei, de Villiers, Sabina, Pentel, Paul, Zhang, Jianfei, Dorn, Harry, Ehrich, Marion, Zhang, Chenming

Journal:

Journal of Biomedical Nanotechnology

Year:

2015

Language:

english

File:

PDF, 9.50 MB

english, 2015

7

Bupropion and Naltrexone for Smoking Cessation: A Double-Blind Randomized Placebo-Controlled Clinical Trial

Mooney, Marc E., Schmitz, Joy M., Allen, Sharon, Grabowski, John, Pentel, Paul, Oliver, Andrew, Hatsukami, Dorothy K.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2016

Language:

english

File:

PDF, 758 KB

english, 2016

8

Effect of adjuvant release rate on the immunogenicity of nanoparticle-based vaccines: A case study with a nanoparticle-based nicotine vaccine

Zhao, Zongmin, Hu, Yun, Harmon, Theresa, Pentel, Paul, Ehrich, Marion, Zhang, Chenming

Journal:

Molecular Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 2.01 MB

english, 2019

9

Tobacco extract but not nicotine impairs the mechanical strength of fracture healing in rats

Martin Skott, Troels T. Andreassen, Michael Ulrich-Vinther, X. Chen, Dan E. Keyler, Mark G. LeSage, Paul R. Pentel, Joan E. Bechtold, Kjeld Soballe

Journal:

Journal of Orthopaedic Research

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

10

Cloning, expression, and purification of an anti-desipramine single chain antibody in NS/0 myeloma cells

Kirsten Kitchin, Gaofeng Lin, Weilin L. Shelver, Michael P. Murtaugh, Paul R. Pentel, Susan M. Pond, Janelle C. Oberst, John E. Humphrey, John M. Smith, Michael C. Flickinger

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 925 KB

english, 1995

11

Large scale production and purification of paraquat and desipramine monoclonal antibodies and their fab fragments

Mark Bowles, Shane C. Johnston, Deric D. Schoof, Paul R. Pentel, Susan M. Pond

Journal:

International Journal of Immunopharmacology

Year:

1988

Language:

english

File:

PDF, 537 KB

english, 1988

12

Drug-specific F(ab′)2 fragment reduces desipramine cardiotoxicity in rats

Gregory J. Brunn, Daniel E. Keyler, Catherine A. Ross, Susan M. Pond, Paul R. Pentel

Journal:

International Journal of Immunopharmacology

Year:

1991

Language:

english

File:

PDF, 780 KB

english, 1991

13

Bacterial expression and characterization of an anti-desipramine single-chain antibody fragment

Gaofeng Lin, Paul R. Pentel, Weilin L. Shelver, Daniel E. Keyler, Catherine A. Ross, Yoko Hieda, Michael C. Flickinger, Christopher A. Pennell, Michael P. Murtaugh

Journal:

International Journal of Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

14

Asystole complicating physostigmine treatment of tricyclic antidepressant overdose

Paul Pentel, Charles D. Peterson

Journal:

Annals of Emergency Medicine

Year:

1980

Language:

english

File:

PDF, 1.44 MB

english, 1980

15

Authors' reply

Paul Pentel, Charles Peterson

Journal:

Annals of Emergency Medicine

Year:

1981

Language:

english

File:

PDF, 253 KB

english, 1981

16

Management of cocaine poisoning

Kent Olson, Neal L. Benowitz, Paul Pentel

Journal:

Annals of Emergency Medicine

Year:

1983

Language:

english

File:

PDF, 237 KB

english, 1983

17

Reduction of Desipramine Cardiotoxicity and Prolongation of Survival in Rats With the Use of Polyclonal Drug-Specific Antibody Fab Fragments

Paul R Pentel, William Scarlett, Catherine A Ross, John Landon, Ahmed Sidki, Daniel E Keyler

Journal:

Annals of Emergency Medicine

Year:

1995

Language:

english

File:

PDF, 772 KB

english, 1995

18

Effects of carbamazepine on acute responses to smoked cocaine-base in human cocaine users

Dorothy Hatsukami, Robert Keenan, James Halikas, Paul R. Pentel, Lisa Hartman Brauer

Journal:

Psychopharmacology

Year:

1991

Language:

english

File:

PDF, 673 KB

english, 1991

19

Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats

Mark G. LeSage, Daniel E. Keyler, Yoko Hieda, Greg Collins, Danielle Burroughs, Chap Le, Paul R. Pentel

Journal:

Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

20

Prevalence, magnitude, and correlates of an extinction burst in drug-seeking behavior in rats trained to self-administer nicotine during unlimited access (23

Andrew C. Harris, Paul R. Pentel, Mark G. LeSage

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

21

Effects of pregnancy on nicotine self-administration and nicotine pharmacokinetics in rats

Mark G. LeSage, Daniel E. Keyler, Danielle Burroughs, Paul R. Pentel

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

22

Correlates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit dose

Andrew C. Harris, Paul R. Pentel, Mark G. LeSage

Journal:

Psychopharmacology

Year:

2009

Language:

english

File:

PDF, 350 KB

english, 2009

23

A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats

Andrew C. Harris, Paul R. Pentel, Danielle Burroughs, Mylissa D. Staley, Mark G. LeSage

Journal:

Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 704 KB

english, 2011

24

Cotinine: effects with and without nicotine

D. Hatsukami, Paul R. Pentel, Joni Jensen, David Nelson, Sharon S. Allen, Anne Goldman, Donna Rafael

Journal:

Psychopharmacology

Year:

1998

Language:

english

File:

PDF, 307 KB

english, 1998

25

Effects of dynorphin A(1–13) on opiate withdrawal in humans

S. Specker, Winai Wananukul, Dorothy Hatsukami, Kim Nolin, Lyn Hooke, Mary Jeanne Kreek, Paul R. Pentel

Journal:

Psychopharmacology

Year:

1998

Language:

english

File:

PDF, 155 KB

english, 1998

26

Effects of cotinine on cigarette self-administration

D. Hatsukami, Benjamin Lexau, David Nelson, Paul R. Pentel, Mehmet Sofuoglu, Anne Goldman

Journal:

Psychopharmacology

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

27

Reply

Keenan, Robert M., Hatsukami, Dorothy K., Pentel, Paul R., Thompson, Timothy N., Grillo, Michael A.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 247 KB

english, 1995

28

Propranolol antagonism of phenylpropanolamine-induced hypertension

Pentel, Paul R, Asinger, Richard W, Benowitz, Neal L

Journal:

Clinical Pharmacology & Therapeutics

Year:

1985

Language:

english

File:

PDF, 405 KB

english, 1985

29

Reply

Pentel, Paul, Asinger, Richard, Benowitz, Neal

Journal:

Clinical Pharmacology & Therapeutics

Year:

1986

Language:

english

File:

PDF, 172 KB

english, 1986

30

Individual variability in the blood pressure response to intravenous phenylpropanolamine: A pharmacokinetic and pharmacodynamic investigation

O'Connell, Mary Beth, Pentel, Paul R, Zimmerman, Cheryl L

Journal:

Clinical Pharmacology & Therapeutics

Year:

1989

Language:

english

File:

PDF, 503 KB

english, 1989

31

Pharmacodynamic effects of cotinine in abstinent cigarette smokers

Keenan, Robert M, Hatsukami, Dorothy K, Pentel, Paul R, Thompson, Timothy N, Grillo, Michael A

Journal:

Clinical Pharmacology & Therapeutics

Year:

1994

Language:

english

File:

PDF, 1.33 MB

english, 1994

32

Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats

Andrew C. Harris, Irina Stepanov, Paul R. Pentel, Mark G. LeSage

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 323 KB

english, 2012

33

Methodological issues in the administration of multiple doses of smoked cocaine-base in humans

Dorothy K. Hatsukami, Paul R. Pentel, John Glass, Rick Nelson, Lisa H. Brauer, Ross Crosby, Karen Hanson

Journal:

Pharmacology Biochemistry and Behavior

Year:

1994

Language:

english

File:

PDF, 842 KB

english, 1994

34

Reduced nicotine distribution from mother to fetal brain in rats vaccinated against nicotine: Time course and influence of nicotine dosing regimen

Daniel E. Keyler, Matthew B. Dufek, Andrew D. Calvin, Thomas J. Bramwell, Mark G. LeSage, Donna E. Raphael, Cathy A. Ross, Chap T. Le, Paul R. Pentel

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 336 KB

english, 2005

35

Effects of nicotine-specific antibodies, Nic311 and Nic-IgG, on the transfer of nicotine across the human placenta

Ilona A. Nekhayeva, Tatiana N. Nanovskaya, Paul R. Pentel, Dan E. Keyler, Gary D.V. Hankins, Mahmoud S. Ahmed

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

36

Reinstatement of nicotine self-administration in rats by presentation of nicotine-paired stimuli, but not nicotine priming

Mark G. LeSage, Danielle Burroughs, Matthew Dufek, Daniel E. Keyler, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2004

Language:

english

File:

PDF, 211 KB

english, 2004

37

Effects of nicotine withdrawal on performance under a progressive-ratio schedule of sucrose pellet delivery in rats

Mark G. LeSage, Danielle Burroughs, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

38

Effects of maternal intravenous nicotine administration on locomotor behavior in pre-weanling rats

Mark G. LeSage, Erianne Gustaf, Matthew B. Dufek, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2006

Language:

english

File:

PDF, 328 KB

english, 2006

39

Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats

Samuel A. Roiko, Andrew C. Harris, Mark G. LeSage, Daniel E. Keyler, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

40

Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats

Andrew C. Harris, Christina Mattson, Mark G. LeSage, Daniel E. Keyler, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2010

Language:

english

File:

PDF, 548 KB

english, 2010

41

Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist

Mark G. LeSage, David Shelley, Marco Pravetoni, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2012

Language:

english

File:

PDF, 509 KB

english, 2012

42

High-level secretion of two antibody single chain Fv fragments by Pichia pastoris

Patrick Eldin, Mary E Pauza, Yoko Hieda, Gaofeng Lin, Michael P Murtaugh, Paul R Pentel, Christopher A Pennell

Journal:

Journal of Immunological Methods

Year:

1997

Language:

english

File:

PDF, 192 KB

english, 1997

43

Passive immunization against nicotine prevents nicotine alleviation of nicotine abstinence syndrome

David H Malin, J.Ronald Lake, Andy Lin, Michael Saldaña, Laura Balch, M.L.Laredo Irvin, Hishara Chandrasekara, Candice L Alvarado, Yoko Hieda, Dan E Keyler, Paul R Pentel, Sofiane Ennifar, Lisa E Bash

Journal:

Pharmacology Biochemistry and Behavior

Year:

2001

Language:

english

File:

PDF, 281 KB

english, 2001

44

Continuous nicotine infusion reduces nicotine self-administration in rats with 23-h/day access to nicotine

Mark G. LeSage, Dan E. Keyler, Don Shoeman, Donna Raphael, Gregory Collins, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2002

Language:

english

File:

PDF, 290 KB

english, 2002

45

Lack of effect of 5HT3 antagonist in mediating subjective and behavioral responses to cotinine

Dorothy K. Hatsukami, Joni Jensen, Lisa H. Brauer, Marc Mooney, Susan Schulte, Mehmet Sofuoglu, Paul R. Pentel

Journal:

Pharmacology Biochemistry and Behavior

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

46

Safety of Cotinine in Humans: Physiologic, Subjective, and Cognitive Effects

Dorothy K Hatsukami, Michael Grillo, Paul R Pentel, Cheryl Oncken, Robin Bliss

Journal:

Pharmacology Biochemistry and Behavior

Year:

1997

Language:

english

File:

PDF, 217 KB

english, 1997

47

Effects of Labetalol Treatment on the Physiological and Subjective Response to Smoked Cocaine

Mehmet Sofuoglu, Scott Brown, David A Babb, Paul R Pentel, Dorothy K Hatsukami

Journal:

Pharmacology Biochemistry and Behavior

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

48

A Nicotine Conjugate Vaccine Reduces Nicotine Distribution to Brain and Attenuates Its Behavioral and Cardiovascular Effects in Rats

Paul R Pentel, David H Malin, Sofiane Ennifar, Yoko Hieda, Dan E Keyler, J.Ronald Lake, Judit R Milstein, Lisa E Basham, R.Todd Coy, J.William D Moon, Robert Naso, Ali Fattom

Journal:

Pharmacology Biochemistry and Behavior

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

49

Effect of hypertonic sodium bicarbonate on encainide overdose

Paul R. Pentel, Steven R. Goldsmith, David M. Salerno, Stanley A. Nasraway, David W. Plummer

Journal:

The American Journal of Cardiology

Year:

1986

Language:

english

File:

PDF, 408 KB

english, 1986

50

Redistribution into plasma of tracer doses of desipramine by anti-desipramine antiserum in rats

Paul Pentel, Susan M. Pond, Deric Schoof

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 455 KB

english, 1987

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